Meta-analysis of microRNA profiling data does not reveal a consensus signature for B cell acute lymphoblastic leukemia.

B cell acute lymphoblastic leukemia (B-ALL) is the most prevalent pediatric cancer. MicroRNAs (miRNAs) are 18-22nt non-coding transcripts shown to be essential for the development of many cancers. While some miRNAs are reportedly expressed differentially between healthy and B-ALL, no studies have reported a consensus miRNA signature.

The Association Between Waist Circumference and FITNESSGRAM® Aerobic Capacity Classification in Sixth-Grade Children.

Cardiorespiratory fitness is often assessed through measures of maximal oxygen uptake, sometimes referred to as aerobic capacity (26). The importance of adequate aerobic capacity for optimal health has been observed in numerous studies examining both adults (1,2,20) and children (17,24). An increased risk of overweight and metabolic syndrome in adults can result from a reduction in aerobic capacity from childhood to adolescence (4,11).

Comparison of Academic and Behavioral Performance between Athletes and Non-athletes.

The Toronto Charter for Physical Activity (2010) and several national physical activity plans advocate sports participation as an important part of population targeted physical activity for youth. Emerging research evidence also suggests that sports participation during adolescents is linked to significant positive correlations with academic and behavioral performance. The purpose of this study was to compare academic and behavioral performance between male and female public school athletes (Total N=11,139; 38% Female) and non-athletes (Total N=23,891; 52% Female) in a convenient, ethnicity diverse, sample (grades 7-12) from the state of Texas (USA).

FITNESSGRAM® Friday: A Middle School Physical Activity and Fitness Intervention.

Texas Senate Bill 530 (2007) mandated fitness assessment as part of the annual K-8 Physical Education (PE) curricula, yet no studies have reported interventions designed to improve and quantify individual student passing rates or individual school performance. Students (Total 2008-2010 N=1484; 729 females, 755 males; mean age = 11.85 y; mean BMI = 22.

Lateral pallidotomy exacerbates akinesia in the Parkinsonian patient.

Despite the recent resurgence of interest in the use of pallidotomy for the treatment of Parkinson's disease, there remains considerable debate about the optimal lesion site. Although the current understanding of the neural mechanisms underlying Parkinsonism would suggest that the medial pallidum is the logical site for alleviation of symptoms, some surgeons still advocate lesions in the lateral pallidum. We report the case of such a lesion placement verified pathologically, which resulted in exacerbation of akinesia postoperatively.