Publications by authors named "W Sperker"
Article Synopsis
- There are rare mitochondrial disorders linked to biallelic variations that cause kidney failure, tremors, hearing loss, seizures, and intellectual disability, with only two prior studies noted.
- A case study of a man showed symptoms like ataxia, kidney failure, and hearing loss, revealing a novel variant through whole genome sequencing.
- The findings highlighted significant mitochondrial abnormalities, underpinning the connection between the newly identified variant and a slowly progressive form of cerebellar ataxia, contributing to the understanding of this genetic condition.
Unlabelled: Therapeutic apheresis (TA) as a treatment for antibody-associated vasculitis (AAV) was questioned by the PEXIVAS although the MEPEX study favored TA. The aim of this study was to evaluate the efficacy of TA to improve renal function in patients consecutively included in the WAA-apheresis registry versus patients not treated with TA.
Materials And Methods: Included were 192 patients that suffered from anti-glomerular basement membrane disease (anti-GBM, n = 28) and antineutrophil cytoplasmic antibody-associated vasculitis of MPO or PR3 origin.
Aim: When performing acute onset dialysis after insertion of catheters for peritoneal dialysis, pain exists and tunnel infections may develop. This study investigated whether patients benefit from the use of a surgical girdle and specific dressing postoperatively to prevent pain and tunnel infections.
Materials And Methods: In 85 consecutive patients, the development of tunnel infections was followed.
We developed a technique for direct start of peritoneal dialysis. Using a coiled or straight Tenckhoff catheter often results in obstruction of flow. A self-locating Wolfram catheter is on the market.
View Article and Find Full Text PDFObjective: To explore the morphological and functional effect of selective and non-selective endothelin (ET)-receptor blockade in coronary artery disease (CAD).
Design: Prospective randomised controlled trial.
Setting: University hospital.