Publications by authors named "W Sieling"

Article Synopsis
  • Blood cultures are often collected from adults with acute respiratory infections (ARI) admitted to the hospital, but the actual rate of secondary bacteremia in these patients with respiratory syncytial virus (RSV) is not well understood.
  • This study aimed to investigate the occurrence and causes of secondary bacteremia among hospitalized adult RSV patients, analyzing which factors influence both the presence of bacteremia and the decision to collect blood cultures in the emergency department.
  • The findings revealed that only 6.7% of adults with RSV had secondary bacteremia, primarily from nonrespiratory sources, and that those with asthma or chronic obstructive pulmonary disease were less likely to have bacteremia detected.
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Background: Respiratory syncytial virus (RSV) infections are common in adults, but data describing the cost of RSV-associated hospitalization are lacking due to inconsistency in diagnostic coding and incomplete case ascertainment. We evaluated costs of RSV-associated hospitalization in adult patients with laboratory-confirmed, community-onset RSV.

Methods: We included adults ≥ 18 years of age admitted to three hospital systems in New York during two RSV seasons who were RSV-positive by polymerase chain reaction (PCR) and had more than or equal to two acute respiratory infection symptoms or exacerbation of underlying cardiopulmonary disease.

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Objectives: Respiratory syncytial virus (RSV) causes substantial morbidity and mortality in older adults. We assessed severe clinical outcomes among hospitalized adults that were associated with RSV infections.

Methods: We performed a nested retrospective study in 3 New York City hospitals during 2 respiratory viral seasons, October 2017-April 2018 and October 2018-April 2019, to determine the proportion of patients with laboratory-confirmed RSV infection who experienced severe outcomes defined as intensive care unit (ICU) admission, mechanical ventilation, and/or death.

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