Publications by authors named "W Shehadeh"
Background: Therapeutic dogma has been to treat acne scars with ablative fractional laser no less than 6 months after isotretinoin (ITN) cessation.
Objective: To evaluate the safety and efficacy of fractional ablative CO laser (FACL) in patients treated concurrently with ITN.
Methods: We conducted a prospective split-face randomized control trial in patients treated with FACL concurrently with ITN versus patients treated with FACL 6 months post-ITN treatment.
Article Synopsis
- A study investigated the effectiveness of a hybrid laser combining CO and nonablative 1570 nm lasers for facial rejuvenation, comparing low-to-moderate treatments versus a single aggressive treatment.
- The study involved 44 patients divided into two groups: one receiving a single high-setting treatment and the other getting 2-3 lower-setting treatments, with evaluations by independent physicians.
- Results showed that the group with multiple low-to-moderate treatments had higher patient satisfaction, less downtime (4.3 vs. 7.3 days), and no reported adverse events, while both groups showed a similar overall improvement of 51%-75%.
Background: Hyaluronic acid (HA)-based fillers are effective at mitigating acne scars due to their filling effect. Complexes of high and low molecular weight HA demonstrated a delayed biostimulatory effect.
Objective: The authors sought to compare the results of acne scar treatment using a filler composed of complexes of high and low molecular weight HA versus a traditional cross-linking HA filler.
Netherton syndrome (NS) is a rare disorder of cornification associated with high morbidity. It is caused by bi-allelic mutations in SPINK5 encoding the serine protease inhibitor LEKTI. Previous studies have shown Th17 skewing with IL-23 upregulation in NS, raising the possibility that targeting these inflammatory pathways may alleviate disease manifestations.
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