Publications by authors named "W Sheehan"
This review highlights studies from the past 3 years that add to the understanding of the impact of environmental exposures on allergic disease. These include aeroallergens, air quality, prenatal or early-life exposures, and occupational exposures. Recent studies have focused on the relationship between the environment, the microbiome, and allergic disease, and new therapeutic options have also been reviewed.
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- - The study aimed to assess whether one year of subcutaneous immunotherapy (SCIT) would improve nasal responses to cockroach allergens in urban children with asthma who are sensitive to these allergens.
- - Results indicated that there was no significant improvement in total nasal symptom scores (TNSS) after SCIT compared to a placebo; however, SCIT did result in decreased skin reaction size and increased specific antibody production against the allergen.
- - Overall, while SCIT showed systemic effects by affecting immune responses, it did not change nasal symptoms or transcriptomic responses during allergen exposure.
Article Synopsis
- The study looks at two ways to treat fractures in the upper arm: one is to use a brace and the other is surgery.
- The goal is to see which method works better and costs less for patients.
- The trial will involve 334 adults and will check how people recover, including how much pain they have and how it affects their daily lives.
Aims: There is a lack of published evidence relating to the rate of nonunion seen in occult scaphoid fractures, diagnosed only after MRI. This study reports the rate of delayed union and nonunion in a cohort of patients with MRI-detected acute scaphoid fractures.
Methods: This multicentre cohort study at eight centres in the UK included all patients with an acute scaphoid fracture diagnosed on MRI having presented acutely following wrist trauma with normal radiographs.
Background: Distal radius fractures are common fractures in older adults and associated with increased risk of future functional decline and hip fracture. Whether lower limb muscle strength and balance are impaired in this patient population is uncertain. To help inform rehabilitation requirements, this systematic review aimed to compare lower limb muscle strength and balance between older adults with a distal radius fracture with matched controls, and to synthesise lower limb muscle strength and balance outcomes in older adults with a distal radius fracture.
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