Depressive symptoms as predictors of medical outcomes in HIV infection. Multicenter AIDS Cohort Study.

Objective: To ascertain whether depressive symptoms as determined by the Center for Epidemiologic Studies-Depression scale (CES-D) predict accelerated mortality and worse medical outcomes in patients infected with human immunodeficiency virus (HIV).

Design: Eight-year cohort study with semiannual follow-up.

Setting: Community volunteers.