The carcinoembryonic antigen (CEA) was studied in paraffin sections of 114 benign breast lesions and in 65 tumor-bearing breasts using the indirect immune peroxidase technique. CEA was observed in 21% of the cases studied. In mastopathies without carcinoma it was found in 64%.
View Article and Find Full Text PDFBy means of immunoperoxidase techniques carcinoembryonic antigen (CEA) has been localized first in carcinomas of the gastrointestinal tract and then also in other malignant tissues, such as carcinomas of the female genital tract and the breast. There is still an obvious need for intensive studies of the possible effects which the initial tissue processing, i. e.
View Article and Find Full Text PDFPathol Res Pract
December 1982
It is well known that the concentration of serum CEA correlates best with colorectal carcinomas but less well with other solid tumors. The aim of the present study was to elucidate further the poor relationship between confirmed primary mammary carcinomas and CEA serum levels, 108 of these tumors have hence been studied for their tissular CEA positivity and the results obtained were compared with the CEA serum values found preoperatively in the same patients. Techniques employed were the indirect immunoperoxydase method for the histologic studies and the enzymoimmuno-assay for the serum measurements.
View Article and Find Full Text PDFPathol Res Pract
September 1981
The essential findings obtained by our investigations may be summarized as follows: 1. Taking into account that factual information must be transmitted when teaching and learning pathology, no method can be considered as being clearly superior to any other. 2.
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