Finite element derived femoral strength is a better predictor of hip fracture risk than aBMD in the AGES Reykjavik study cohort.

Hip fractures associated with a high economic burden, loss of independence, and a high rate of post-fracture mortality, are a major health concern for modern societies. Areal bone mineral density is the current clinical metric of choice when assessing an individual's future risk of fracture. However, this metric has been shown to lack sensitivity and specificity in the targeted selection of individuals for preventive interventions.

Correction: On the internal reaction forces, energy absorption, and fracture in the hip during simulated sideways fall impact.

[This corrects the article DOI: 10.1371/journal.pone.

Biofidelic finite element models for accurately classifying hip fracture in a retrospective clinical study of elderly women from the AGES Reykjavik cohort.

Clinical retrospective studies have only reported limited improvements in hip fracture classification accuracy using finite element (FE) models compared to conventional areal bone mineral density (aBMD) measurements. A possible explanation is that state-of-the-art quasi-static models do not estimate patient-specific loads. A novel FE modeling technique was developed to improve the biofidelity of simulated impact loading from sideways falling.

On the internal reaction forces, energy absorption, and fracture in the hip during simulated sideways fall impact.

The majority of hip fractures have been reported to occur as a result of a fall with impact to the greater trochanter of the femur. Recently, we developed a novel cadaveric pendulum-based hip impact model and tested two cadaveric femur-pelvis constructs, embedded in a soft tissue surrogate. The outcome was a femoral neck fracture in a male specimen while a female specimen had no fracture.

Strain rate dependency of bovine trabecular bone under impact loading at sideways fall velocity.

There is currently a knowledge gap in scientific literature concerning the strain rate dependent properties of trabecular bone at intermediate strain rates. Meanwhile, strain rates between 10 and 200/s have been observed in previous dynamic finite element models of the proximal femur loaded at realistic sideways fall speeds. This study aimed to quantify the effect of strain rate (ε̇) on modulus of elasticity (E), ultimate stress (σ), failure energy (U), and minimum stress (σ) of trabecular bone in order to improve the biofidelity of material properties used in dynamic simulations of sideways fall loading on the hip.