Revision Total Elbow Arthroplasty.

Despite improvements in our understanding of elbow biomechanics and implant design, early revision are higher following total elbow arthroplasty (TEA) compared with hip and knee arthroplasty. Revision TEA remains a standard but technically challenging procedure with the potential for substantial morbidity. This review discusses the diagnosis and management of the failed primary TEA.

Development of a Ratiometric Fluorescent Cu(II) Indicator Based on Poly(-isopropylacrylamide) Thermal Phase Transition and an Aminopyridyl Cu(II) Ligand.

An aqueous Cu and Zn indicator is reported based on copolymerizing aminopyridine ligands and the environment-sensitive dansyl fluorophore into the responsive polymer poly(N-isopropylacrylamide) (PNIPAm). The metal ion binding creates charge and solvation that triggers PNIPAm's thermal phase transition from hydrophobic globule to hydrophilic open coil. As a basis for sensing the metal-binding, the dansyl fluorescence emission spectra provide a signal at ca.

Mission impossible? Spatial context relearning following a target relocation event depends on cue predictiveness.

Visual search for a target is faster when the spatial layout of distractors is repeatedly encountered, illustrating that statistical learning of contextual invariances facilitates attentional guidance (contextual cueing; Chun & Jiang, 1998, Cognitive Psychology, 36, 28-71). While contextual learning is usually relatively efficient, relocating the target to an unexpected location (within an otherwise unchanged search layout) typically abolishes contextual cueing and the benefits deriving from invariant contexts recover only slowly with extensive training (Zellin et al., 2014, Psychonomic Bulletin & Review, 21(4), 1073-1079).

Visualizing genomic data: The mixing perspective.

We report on a novel way to visualize genomic data. By considering genome coding sequences, cds, as sets of the N=61 non-stop codons, one obtains a partition of the total number of codons in each cds. Partitions exhibit a statistical property known as mixing character which characterizes how mixed the partition is.