Publications by authors named "W Rodrigues"
Ticks have coevolved with their hosts over millions of years, developing the ability to evade hemostatic, inflammatory, and immunological responses. Salivary molecules from these vectors bind to cytokines, chemokines, antibodies, complement system proteins, vasodilators, and molecules involved in coagulation and platelet aggregation, among others, inhibiting or blocking their activities. Initially studied to understand the complexities of tick-host interactions, these molecules have been more recently recognized for their potential clinical applications.
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- The study explored how different Eucalyptus clones responded to drought conditions to help select resilient varieties for climate change.
- The C2 clone exhibited superior drought tolerance by maintaining stable CO2 assimilation and higher water use efficiency compared to other clones, despite reduced water availability.
- Chlorophyll a fluorescence measurements proved more effective in indicating drought tolerance than traditional gas-exchange parameters in evaluating the clones' performance under water stress.
High-fat diet during lactation, as opposed to during adolescence or gestation, programs cardiometabolic and autonomic dysfunctions in adult offspring.
Brain Res
November 2024
The Developmental Origins of Health and Disease (DOHaD) concept has been established for three decades. Many studies have shown that, besides pregnancy, other plastic phases (mainly preconception, lactation, and infancy-adolescence) are also sensitive to environmental changes, including nutritional conditions, that can program health or disease later in life. This study compared the susceptibility of the gestation, lactation and adolescence to a high-fat diet (HFD) intervention to program rats into autonomic nervous system imbalance and cardiometabolic dysfunction in adulthood.
View Article and Find Full Text PDFThis article aims to analyze the performance of the Brazilian Unified National Health System (SUS, acronym in Portuguese) hospital network based on the national databases of the Brazilian Hospital Information System (SIH, acronym in Portuguese) and the Brazilian National Registry of Health Establishments (CNES, acronym in Portuguese). The research used a set of indicators covering the production of admissions, the profile, quality and performance of care, associated with hospital size and legal nature. For data analysis, the Analysis of Variance with Tukey-Kramer test was used to highlight the differences between public and private hospitals, the moderation analysis to verify the effect of hospital size and the Pabon Lasso model to integrate the results.
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- Prolonged pleural effusion/chylothorax (PPE/C) is a complication in pediatric cardiac surgery that has not been thoroughly studied, prompting this investigation into its incidence, risk factors, and impact on outcomes.
- A multicentre study collected data on multiple post-operative complications across 5 UK hospitals, finding that PPE/C occurred in 6.5% of patients, typically 6 days after surgery, and increased mortality primarily in patients with multiple other complications.
- The study concludes that while PPE/C is associated with increased mortality, it does not significantly extend hospital length of stay in cases with multiple complications, highlighting the need for effective prevention and management strategies for PPE/C in complex post-operative care.