Publications by authors named "W Rehwald"
Article Synopsis
- This study compares the image quality and methods for measuring infarct size between a new technique called MT-FIDDLE and the standard bright-blood LGE cardiac MRI in patients who had a heart attack (STEMI).
- The results indicate that MT-FIDDLE provides significantly better subjective image quality, particularly in terms of confidence for infarct segmentation and blood-pool contrast, with a high concordance in infarct volume measurements compared to bright-blood LGE.
- Ultimately, MT-FIDDLE proved to enhance the ability to differentiate between heart injury (myocardial infarction) and surrounding blood, suggesting it could be a superior imaging method for assessing heart damage after a STEMI.
Purpose: CEST MRI has been used to probe changes in cardiac metabolism via assessment of CEST contrast from Cr. However, B variation across the myocardium leads to spatially variable Cr CEST contrast in healthy myocardium.
Methods: We developed a spatial-spectral (SPSP) saturation pulsed CEST protocol to compensate for B variation.
Background The relationship between papillary muscle infarction (papMI) and the culprit coronary lesion has not been fully investigated. Delayed enhancement cardiac MRI may detect papMI, yet its accuracy is unknown. Flow-independent dark-blood delayed enhancement (FIDDLE) cardiac MRI has been shown to improve the detection of myocardial infarction adjacent to blood pool.
View Article and Find Full Text PDFDespite clinical use of late gadolinium enhancement (LGE) for two decades, an efficient, robust fat suppression (FS) technique still does not exist for this CMR mainstay. In ischemic and non-ischemic heart disease, differentiating fibrotic tissue from infiltrating and adjacent fat is crucial. Multiple groups have independently developed an FS technique for LGE, double spectral attenuated inversion recovery (DSPAIR), but no comprehensive evaluation was performed.
View Article and Find Full Text PDFObjectives: The purpose of this study was to assess whether the presence and extent of fibrosis changes over time in patients with nonischemic, dilated cardiomyopathy (DCM) receiving optimal medical therapy and the implications of any such changes on left ventricular ejection fraction (LVEF) and clinical outcomes.
Background: Myocardial fibrosis on cardiovascular magnetic resonance (CMR) imaging has emerged as important risk marker in patients with DCM.
Methods: In total, 85 patients (age 56 ± 15 years, 45% women) with DCM underwent serial CMR (median interval 1.