Publications by authors named "W Rauhe"

Background: Cardiac resynchronization therapy (CRT) is a cornerstone treatment for heart failure, yet the optimal pacing mode remains uncertain. This study investigates the impact of DDDR (rate-adaptive atrial support) versus VDD pacing modes on functional capacity and echocardiographic outcomes in patients with CRT-defibrillators.

Methods: In a multicenter, double-blind, crossover trial, 26 sinus rhythm patients undergoing CRT-defibrillator implantation were randomized to DDDR at 60 beats-per-minute or VDD at 30 beats-per-minute.

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Article Synopsis
  • hiPSC-CMs are being used to model arrhythmogenic cardiomyopathy (ACM), a genetic heart disease with varying symptoms due to incomplete penetrance and variable expressivity.
  • Six hiPSC lines were created from blood samples of ACM patients, asymptomatic carriers, and a healthy control, with detailed analysis revealing significant molecular and functional differences among these cell lines.
  • The study suggests that hiPSC-CMs effectively demonstrate how ACM can manifest differently in individuals, making them a valuable tool for researching the disease's incomplete penetrance.
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Background: The association between QRS narrowing and response to cardiac resynchronization therapy (CRT) has been investigated by several studies, but their findings remain inconclusive. Aim of our study was to explore the relationship between QRS Index and echocardiographic response to CRT.

Methods: This multicenter, retrospective analysis included 326 consecutive patients (mean age was 70.

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Background: The identification of a "low-voltage bridge" to guide ablation of atrioventricular nodal reentry tachycardia (AVNRT) has been described as a safe and effective strategy in children. We investigated the presence of a low-voltage bridge in adult patients undergoing AVNRT ablation, to evaluate its anatomical correspondence with the successful ablation site. We also investigated the possible correlations between Koch's triangle anatomy and patients' biometric characteristics.

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Background: A better selection of patients with left bundle branch block (LBBB) might increase the response to cardiac resynchronization therapy (CRT). The aim of the study was to investigate the association between the Strauss criteria, absence of S wave in V-V the Selvester score and response to CRT.

Methods And Results: The retrospective analysis included all consecutive patients having undergone implantation of biventricular defibrillators in primary prevention between 2018 and 2020.

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