Publications by authors named "W R Pace"
Background: Preserved ratio impaired spirometry (PRISm) represents a population with spirometry results that do not meet standardized COPD obstruction criteria, yet present with high respiratory symptom burden and might benefit from respiratory management and treatment. We aimed to determine prevalence of PRISm in US primary care patients diagnosed with COPD, describe their demographic, clinical, and CT scan characteristics.
Methods: An observational registry study utilizing the US APEX COPD registry, composed of patients diagnosed with COPD aged 35+ years.
Objective: The Person Empowered Asthma Relief (PREPARE) study found that as-needed inhaled corticosteroid (ICS) supplementation combined with participants' usual controller and rescue therapy reduced asthma exacerbations for Black and Hispanic/Latinx individuals. We aimed to determine whether treatment assignment to the intervention group (Patient Activated Reliever-Triggered ICS (PARTICS)) versus the control group (usual care) influenced controller therapy based on clinicians' written prescriptions.
Design: Secondary data analysis of electronic health record data of a pragmatic, open-label, patient-level randomised trial.
Background: The COVID-19 pandemic has reshaped healthcare delivery worldwide.
Objective: To explore potential changes in the reasons for visits and modality of care in primary care settings through the International Consortium of Primary Care Big Data Researchers (INTRePID).
Methods: We conducted a cross-sectional, retrospective study from 2018-2021.
Article Synopsis
- Behavioral and mental health disorders are prevalent among children, adolescents, and young adults, leading to increased use of medications, but there’s limited research on the combinations of these drugs in outpatient settings, particularly in New York Medicaid.
- In a study of over 2.4 million Medicaid enrollees under 21 from 2014, about 5.8% were prescribed BMH medications, with 37.8% of those engaged in polypharmacy, resulting in thousands of distinct drug combinations.
- Although contraindicated drug pairs were relatively rare among those prescribed BMH medications, the study identified risks, particularly related to prolonged QT intervals and serotonin syndrome, emphasizing the need for clinicians to carefully