Do we still need a canary in the coal mine for laboratory animal facilities? A systematic review of environmental health monitoring versus soiled bedding sentinels.

Introduction: Despite increasing evidence that Environmental Health Monitoring (EHM) is an effective method to perform rodent colony health surveillance, promotes the 3Rs as a Replacement, is comparable or reduces cost, and demonstrates labor benefits, many research institutions continue to use live Soiled Bedding Sentinels (SBS). Some veterinarians and others responsible for rodent colony health monitoring remain cautious of the evidence supporting this new technology. Therefore, our objective was to perform a formal systematic review to identify, summarize, and evaluate the research on the efficacy of EHM as compared to SBS.

Viral RNA Interactome: The Ultimate Researcher's Guide to RNA-Protein Interactions.

RNA molecules in the cell are bound by a multitude of RNA-binding proteins (RBPs) with a variety of regulatory consequences. Often, interactions with these RNA-binding proteins are facilitated by the complex secondary and tertiary structures of RNA molecules. Viral RNAs especially are known to be heavily structured and interact with many RBPs, with roles including genome packaging, immune evasion, enhancing replication and transcription, and increasing translation efficiency.

Fishy business in Seattle: Salmon mislabeling fraud in sushi restaurants vs grocery stores.

Salmon is the most commonly consumed finfish in the United States of America (USA), and the mislabeling of salmon is a widespread problem. Washington State is a global supplier of wild-caught Pacific salmon and local salmon mislabeling results in substantial economic, ecological, and cultural impacts. Previous studies in Washington State identified high levels of mislabeled salmon in both markets and restaurants, resulting in local legislation being passed that requires proper labeling of salmon products, including identifying it as wild-caught or farm-raised.

Evaluating a Reduction in Treatment Duration of Ivermectin Diet for Fur Mite () Eradication in Mice.

Murine fur mites are commonly excluded in modern research animal programs, yet infestations continue to persist due to challenges in detection and control. Because all diagnostic methods and treatment options have limitations, programs must make many operational decisions when trying to eradicate these ectoparasites. The primary aim of this study was to assess various durations of treatment time with an ivermectin-compounded diet in eliminating in mice as determined by PCR testing and pelt examination.