[Tuberculosis luposa of the face and gluteal-femoral region in a 79 year old patient].

A case of a 79 year old woman with tuberculosis luposa in whom the first cutaneous changes occurred at her young age and it was properly diagnosed only after 50 years.

[Molecular structure of renin-angiotensin-aldosterone system].

The application of novel investigative techniques has demonstrated that the RAA system is one of the major regulators of blood pressure and fluid and electrolyte homeostasis. There is evidence that local RAA systems exist. In this paper we have presented molecular bases of RAA system structure-genomic analysis, tissue distribution, regulation and pharmacological implications.

[Losartan: angiotensin II type 1 receptor antagonist].

The angiotensin II (A II) type 1 receptor (AT1) antagonists represent a new pharmacologic class of drugs. These drugs antagonize A II induced biologic actions. Initial clinical trials suggest that these drugs are effective in the treatment of essential hypertension and hypertensive patients with renal disease.

[Insulin sensitivity in NIDDM patients with normo- and microalbuminuria].

There is contradictory information relating to insulin sensitivity in NIDDM patients with microalbuminuria. The numerous clinical and epidemiological investigations have revealed a greater insulin resistance in these patients. However on the ground of the Nielsen and co-workers observations it has been ascertained that the level of insulin sensitivity is similar in exactly selected NIDDM patients with normo- and microalbuminuria.

[Triiodothyroxine (T3), thyroxine (T4), thyreotropine (TSH) and myoglobin levels in patients with myasthenia gravis].

T3, T4, TSH and myoglobin levels were determined in 14 patients with myasthenia gravis and compared with thirty one healthy control subjects. Significant decrease of myoglobin concentration and increase T3, T4 levels as compared to control group was found. TSH concentration was in normal range.