Publications by authors named "W Plotek"

Article Synopsis
  • - Multi-organ dysfunction in critically ill patients is largely driven by inflammation, which directly impacts the severity of organ damage.
  • - Managing this inflammation involves a team effort, including using antibiotics, providing respiratory and circulatory support, and correcting blood coagulation issues, but effective anti-inflammatory drugs are still debated.
  • - Xanthohumol (Xn), a natural compound from hops, shows promise as an anti-inflammatory agent due to its ability to inhibit inflammatory pathways and boost antioxidant activity, suggesting it could be beneficial in treating critically ill patients.
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Article Synopsis
  • Patients with severe chronic pain from knee osteoarthritis (KO) underwent pulsed radiofrequency ablation (pRFA) of the genicular nerves, with a study of 96 participants evaluating its efficacy and safety.
  • A combination of lidocaine and dexamethasone was used during the pRFA procedure, and patients were assessed over 12 months, showing a successful nerve identification rate of 90.62%.
  • Results indicated that 64.06% experienced a 50% or more reduction in pain, lasting an average of 7.5 months, with outcomes potentially influenced by patient age, sex, and body mass index (BMI).
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Background: Polycystic ovary syndrome (PCOS) is a chronic endocrinopathy characterized by oligo- or anovulation, clinical and/or biochemical markers of hyperandrogenism, and polycystic ovaries, and it is associated with an increased prevalence of depression. Research conducted on psychiatric patients has shown correlations between depression and decreased cognitive function. The aim of this study was to examine the possible mediation of the time perspective (TP) in the development of depressive symptoms in patients with PCOS.

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Brain injury, especially traumatic brain injury (TBI), may induce severe dysfunction of extracerebral organs. Cardiac dysfunction associated with TBI is common and well known as the brain-heart crosstalk, which broadly refers to different cardiac disorders such as cardiac arrhythmias, ischemia, hemodynamic insufficiency, and sudden cardiac death, which corresponds to acute disorders of brain function. TBI-related cardiac dysfunction can both worsen the brain damage and increase the risk of death.

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