Publications by authors named "W Pabo"
Article Synopsis
- There has been an increase in Monkeypox (Mpox) cases globally, prompting a study on healthcare workers' understanding of its transmission, prevention, and response in Cameroon.
- An online survey was conducted with 342 healthcare workers, revealing that while over 90% were aware of Mpox, only 12.9% had excellent knowledge and 42.1% had good knowledge of the disease.
- The findings suggest a need for capacity-building programs to enhance healthcare workers' education on Mpox to ensure effective response to this and similar emerging diseases.
Acquired drug resistance (ADR) is common among adolescents living with perinatal HIV (APHI) in sub-Saharan Africa (SSA). Personalized management has the potential to improve pediatric antiretroviral therapy (ART), even in the presence of long-term treatment and HIV-1 subtype diversity. We sought to evaluate the effect of HIV-1 mutational profiling on immuno-virological response and ADR among APHI.
View Article and Find Full Text PDFIntroduction: The success of antiretroviral therapy (ART) has changed HIV from a deadly to a chronic infection, thus increasing the transitioning from infancy toward adulthood. However, the virostatic nature of antiretrovirals maintains viruses in sanctuaries, with reactivation potentials. Because current ARTs are very limited for children, the emergence of new HIV epidemics driven by HIV drug-resistance mutations is favoured.
View Article and Find Full Text PDFArticle Synopsis
- Non-pharmaceutical interventions, like hygiene measures and lockdown adherence, were assessed in a survey of 971 respondents in Yaounde, Cameroon, focusing on COVID-19 preventive practices and SARS-CoV-2 exposure through IgG tests from October to November 2020.
- The survey revealed that hygiene rules were largely followed (93.8%), while only 49.1% adhered to the "stopped work" measure, with women generally showing higher compliance to preventive practices than men.
- Notably, 31.1% tested positive for SARS-CoV-2, with men having a higher exposure rate, and many participants viewed healthcare facilities as high-risk locations, contributing to low rates of medical consultations and testing.
Characterization of oral candidiasis according to antiretroviral treatment status, immunological and virological profiles among HIV infected patients in two health facilities in Yaoundé-Cameroon: a cross-sectional and analytical study.
Pan Afr Med J
August 2023
Article Synopsis
- The study investigates the prevalence of oral candidiasis among people living with HIV (PLHIV) in Cameroon, differentiating between those on antiretroviral treatment (ART) and those who are ART-naive.
- Results show a significantly higher occurrence of oral candidiasis in ART-naive patients (27.7%) compared to ART-experienced patients (6.3%), indicating a strong link between ART use and decreased incidence.
- The findings highlight that immunodeficiency (CD4<200 cells/mm) and high viral loads (VL≥1000 copies/ml) contribute to the presence of oral candidiasis, emphasizing the need for management strategies for those experiencing immuno-virological failure.