Lens Thickness in Infants and Children with Cataracts.

Purpose: The purpose of this study was to determine the association between lens thickness and cataract in participants aged 0 to 5 years.

Design: This was a prospective, multicenter, case-control study.

Participants: We enrolled 118 participants (171 eyes) aged 0 to 5 years, mean age 14.

Lowe Oculocerebrorenal Syndrome Comparison of Anterior Segment Anatomy in Eyes with and without Glaucoma.

Ultrasound biomicroscopy comparison of two infants with Lowe oculocerebrorenal syndrome, one with glaucoma and one without, found differences in corneal curvature, iris thickness, trabecular-iris angle, and lens morphology are potential glaucoma-associated features.

Bilateral Retinal and Lateral Geniculate Nucleus Infarction in an Adolescent With Influenza.

We describe a 13-year-old female with influenza complicated by bilateral vision loss due to retinal and lateral geniculate nucleus (LGN) infarctions. She continues to have near-total vision loss in her left eye 3.5 years later.

Corneal Structural Changes in Congenital Glaucoma.

Objective: To identify corneal structure differences on quantitative high-frequency ultrasound biomicroscopy (UBM) among subjects with congenital glaucoma compared with controls.

Methods: This prospective case-control study evaluated 180 UBM images from 44 eyes of 30 subjects (18 control and 12 glaucoma, mean age 5.2±8.

Update on the Treatment of Retinoblastoma.

Retinoblastoma (Rb) is the most common pediatric ocular malignancy and accounts for 2% of all childhood cancers. Rb is initiated by a mutation of the 1 tumor suppressor gene and occurs in 2 forms: 1) unilateral and unifocal, characterized by a single tumor in 1 eye, and 2) bilateral or unilateral, multifocal Rb with multiple tumor foci in 1 or both eyes. Rb is a disease of young children and if left untreated can result in visual morbidity as well as systemic mortality.