NivobotulinumtoxinA in the Treatment of Glabellar Lines With or Without Concurrent Treatment of Lateral Canthal Lines in Two Phase 3 Clinical Trials.

Background: Botulinum neurotoxins used in aesthetic medicine require reconstitution before administration, which may be inconvenient and present errors among injectors.

Objectives: Evaluate the efficacy and safety of ready-to-use nivobotulinumtoxinA liquid formulation for the treatment of glabellar lines (GL) with/without treatment of lateral canthal lines (LCL).

Methods: Two multicenter, phase 3, double-blind, randomized trials enrolled participants with moderate-to-severe GL (Study 001) or moderate-to-severe GL+LCL (Study 005).

Texting while driving is a visual problem influenced by phone viewing angle and working distance in young individuals.

Purpose: To investigate the impact of smartphone viewing distance and angle on reaction times.

Design: A prospective, self-controlled, single-center study.

Methods: Participants engaged in a driving simulation facing a large screen with a simulated brake pedal.