Publications by authors named "W Owczarek"
Article Synopsis
- Superficial mucoceles (SM) are benign, small vesicles in the oral mucosa caused by salivary gland duct rupture, often found on the lower lip.
- Immune checkpoint blockade treatments used in cancer can lead to skin-related side effects in 40-50% of patients, with severe cases occurring in 1-2%, such as Stevens-Johnson syndrome.
- A case study highlighted the successful treatment of multiple SM in a patient with squamous cell carcinoma, utilizing plasma and electrocoagulation methods, and aimed to improve understanding of mucosal reactions to cancer therapies.
Article Synopsis
- The study aimed to analyze the demographic and clinical traits of Polish patients with generalized pustular psoriasis (GPP), revealing that most patients are middle-aged women with common comorbidities like hypertension and cardiovascular diseases.
- A total of 90 patients were examined, who had a median GPP duration of 3 years and experienced an average of 2 flares, often requiring hospitalization; main triggers for flares included medications and infections.
- The findings showed significant differences, such as younger patients often having GPP alongside psoriasis vulgaris (PV), highlighting a need for better management due to the high hospitalization rate and recurrent flares.
Human Beta Defensin-2 mRNA and Proteasome Subunit β Type 8 mRNA Analysis, Useful in Differentiating Skin Biopsies from Atopic Dermatitis and Psoriasis Vulgaris Patients.
Agnieszka Terlikowska-Brzósko Ryszard Galus Piotr Murawski Justyna Niderla-Bielińska Izabela Młynarczuk-Biały Witold Owczarek
Int J Mol Sci
August 2024
Article Synopsis
- - The study aimed to create a new diagnostic tool to differentiate between healthy skin, atopic dermatitis (AD), and psoriasis vulgaris (PV) by analyzing specific proteins and their related mRNA levels.
- - Researchers used ELISA and Real-time PCR techniques to measure involucrin (IVL), human β-defensin-2 (hBD-2), and their mRNA from skin biopsies of patients and healthy controls.
- - The findings indicated that hBD-2 mRNA and PSMB8 mRNA levels were key indicators for distinguishing between the different skin conditions, with hBD-2 mRNA alone being effective in identifying inflammatory biopsies from healthy skin.
Article Synopsis
- * A recent study looked at 11 patients with skin tumors, showing that a new FDA-approved plasma device was very effective for treating some of them, leading to great results.
- * Having multiple skin tumors, especially on the face, can be tough for people's feelings and lives, so finding the right treatment that works for each person is really important.
Background: There is limited insight into the current disease burden and everyday clinical management of moderate-to- severe AD in Poland, Czechia, Russia, and Turkiye. Therefore, this study aimed to get information-driven insights regarding the current disease burden and clinical management of patients with moderate-to-severe AD with common and differentiating aspects of the patient journey and establish a consensus.
Methods: In this modified 2-round Delphi panel, 133 questions were asked in total to 27 dermatologists.