Attenuating the Pressor Response to Laryngoscopy and Endotracheal Intubation in Controlled Hypertensives: The Effect of Combining Lidocaine and Magnesium Sulphate.

Background: Laryngoscopy and intubation result in a pressor response which may be deleterious especially in hypertensives, resulting in potentially harmful effects. Many drugs have been used to attenuate this undesirable pressor response to laryngoscopy and intubation in hypertensives; amongst them are magnesium alone in different doses or in combination with lidocaine. However, drug combinations have been found to be more effective than single drug therapy.