[Antibiotic treatment of human actinomykoses (author's transl)].

In the complex aetiology of human actinomykoses, various Actinomyces species, especially A. israelii, play the pathogenetically leading role in the mixed flora so typical for these diseases. A number of other microaerophilic and anaerobic bacteria are also part of such mixed flora.

[Antibiotic resistance of anaerobic bacteria (author's transl)].

Reference data on the overall resistance patterns of anaerobic bacteria are needed since in individual clinical cases susceptibility testing is complicated by the long generation time and difficulties of test conditions. Benzylpenicillin and tetracyclines are the drugs of choice against Clostridium perfringens. Newer cephalosporins are also active, whereas other Clostridium species have been found resistant.

Susceptibility of Bacterium actinomycetem comitans to 45 antibiotics.

The minimal inhibitory concentrations of 45 antimicrobial agents were determined for 14 strains of Bacterium actinomycetem comitans (Actinobacillus actinomycetem-comitans). All the strains showed good susceptibility to tetracyclines and chloramphenicol, but not to lincomycins. Some strains were clearly resistant to penicillins, cephalosporins, and nitroimidazoles.

Susceptibility of Bacteroides melaninogenicus to 45 antibiotics.

The minimal inhibitory concentrations of 45 antimicrobial agents were determined for 13 strains of Bacteroides melaninogenicus. All the strains showed good susceptibility to those agents known to be active against anaerobic gram-negative rods, such as tetracyclines and lincomycins. The lowest MICs were observed with lincomycin, clindamycin, methacycline, doxycycline, minocycline, and erythromycin.

Susceptibility of cutaneous propionibacteria to newer antibiotics.

The minimal inhibitory concentrations of 18 newer antibiotics were determined for 33 strains of cutaneous propionibacteria, i. e., P.