Publications by authors named "W Nan"
Acute myocardial infarction (AMI) and sepsis are the leading causes of high mortality rates in intensive care units. While sepsis frequently affects the cardiovascular system, distinguishing between sepsis-induced cardiomyopathy and AMI remains challenging due to overlapping biomarkers. Misdiagnosis can hinder timely treatment and increase risk of complications.
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- Green mold disease is a significant concern for the production of an important edible mushroom in China, leading to economic losses.
- Two new fungal pathogens were identified as responsible for this disease through analyses of certain genetic markers.
- Pathogenicity tests confirmed the ability of these pathogens to cause symptoms similar to those seen in infected mushrooms, supporting their identification as the causal agents.
Low-dimensional halide perovskites CsCuI have garnered increasing attention for their exceptional luminescent properties, attributed to their stability, high photoluminescence quantum yield (PLQY), and scintillation efficiency. Here, we report the growth of transparent CsCuI crystals via the Bridgman method, emphasizing precise control of melt stoichiometry for optimal performance. Through melt composition optimization, significant improvements in crystal clarity and structural integrity were achieved, enhancing transmittance from 30% to over 80% and achieving nearly 100% PLQY.
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- Viral membrane fusion, driven by membrane fusion proteins (MFPs), is essential for viruses to infect host cells, with cholesterol playing a critical role in this process.
- A study examining the GP64 protein of Bombyx mori nucleopolyhedrovirus (BmNPV) identified six putative CARC motifs, revealing their importance for viral fusion and infection depending on whether the signal peptide is retained or cleaved.
- The research enhances our understanding of viral fusion mechanisms and suggests potential antiviral targets by showing different CARC motifs can function differently in cholesterol-dependent and cholesterol-independent contexts.
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- Impaired endometrial function is a major cause of female infertility, and a new sprayable hydrogel with human endometrial organoid extracellular vesicles (HEO-EVs) aims to address this issue by enhancing uterine function.
- The hydrogel, made of a peptide amphiphile (CPA), combines biocompatible properties with therapeutic EVs sourced from long-term cultured endometrial organoids, promoting rapid gelation and effective application when sprayed onto the uterine lining.
- Research shows that this innovative treatment improves cell growth, reduces free radicals, and boosts fertility in a mouse model with endometrial injury, indicating its potential for targeted therapy in humans.