Publications by authors named "W Naka"
Article Synopsis
- The study focused on the effectiveness of short-term oral fosravuconazole (F-RVCZ) therapy in treating tinea pedis (athlete's foot), administering it for either 1 week or 4 weeks depending on the type of infection.
- Efficacy was assessed at multiple time points after treatment, showing an increase in effectiveness as time progressed, with favorable results for both interdigital/vesicular and hyperkeratotic tinea pedis.
- Adverse reactions were minimal and manageable, suggesting that F-RVCZ may be as effective or superior to existing treatments like terbinafine and itraconazole in Japan.
Onychomycosis, a superficial fungal infection, develops when dermatophytes infect nail plate and beds. Fosravuconazole l-lysine ethanolate (F-RVCZ), a fourth-generation azole antifungal agent with potent antifungal activity and few drug interactions, was highly effective in a clinical trial, with a complete cure rate of 59.4% at 48 weeks after treatment initiation.
View Article and Find Full Text PDFTinea unguium is a common nail disease caused by dermatophytes. Although direct potassium hydroxide (KOH) microscopy and fungal culture are considered the gold standard for diagnosing this disease, their accuracy is insufficient. A lateral flow immunochromatographic assay (LFIA) kit, using a monoclonal antibody against Trichophyton rubrum, was developed and its sensitivity was recently improved 50% in vitro relative to its earlier version.
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