Publications by authors named "W N Fawley"
Article Synopsis
- The study aimed to assess antimicrobial resistance in Europe by analyzing clinical and animal isolates collected in 2018, focusing on emerging ribotypes (RT).
- Fidaxomicin was found to be the most effective antibiotic, whereas specific ribotypes (RT027 and RT181) showed elevated resistance levels against metronidazole, moxifloxacin, and clindamycin.
- The research indicated that increased resistance was primarily in eastern Europe, linked to RT027 and RT181, while northern and western Europe had lower resistance levels overall.
Introduction: Clostridioides difficile infection (CDI) is a leading cause of healthcare-associated (HA) diarrhoea. We retrospectively investigated data from a comprehensive, multidisciplinary C. difficile surveillance programme focusing on hospitalized patients in a tertiary Irish hospital over 10 years.
View Article and Find Full Text PDFClostridioides difficile is the most common cause of antibiotic-associated gastrointestinal infections. Capillary electrophoresis (CE)-PCR ribotyping is currently the gold standard for C. difficile typing but lacks the discriminatory power to study transmission and outbreaks in detail.
View Article and Find Full Text PDFBackground: Gonorrhea is a sexually transmitted infection of global concern. We investigated whole-genome sequencing (WGS) as a tool to measure and enhance partner notification (PN) in gonorrhea management.
Methods: Between May and November 2018, all N.
infection (CDI) remains a major healthcare problem worldwide, however, little is known about CDI epidemiology in Iran. Between December 2004 and November 2018, 3649 stool samples were collected from patients in 69 hospitals and medical centres in Tehran and were cultured for the presence of ; isolates were characterized by PCR ribotyping and toxin genes detection. A total of 582 isolates were obtained and the overall CDI prevalence was 15.
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