Publications by authors named "W Muhuyati"

Article Synopsis
  • - This study examines how certain genetic variations (polymorphisms) in the P-selectin gene (rs1800807 and rs1800808) relate to levels of soluble P-selectin (sPs) in ethnic groups (Han, Uygur, and Kazakh) in Xinjiang, China, particularly in patients with atrial fibrillation (AF) and thromboembolism (TE).
  • - A total of 1,943 participants were included, with various combinations of patients and healthy individuals from the three ethnic groups, and the researchers used Polymerase Chain Reaction and ELISA to analyze genetic variations and measure plasma levels of sPs.
  • - The findings revealed that specific genotypes had significantly different sPs
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We aimed to elucidate the association between connexin 40 (Cx40) genetic polymorphisms and atrial fibrillation (AF) in a Chinese population in Xinjiang comprising Uyghur and Han individuals. We enrolled 275 Uyghur and 305 age- and gender-matched Han subjects, and used polymerase chain reaction to detect single nucleotide polymorphisms (SNPs; -44G/A and +71A/G) in the gene encoding Cx40. A mutation screening was performed by direct sequencing and calculation of genotype and allele frequencies among AF patients and control subjects to determine the relationship between these variants and this condition in Uyghur and Han populations.

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