Publications by authors named "W Miehsler"
Background: Among patients with ulcerative colitis, 30-50% receive corticosteroids within the first five years after diagnosis. We aimed to reconsider their effectiveness in the context of the biologic era.
Methods: In this prospective, multicenter study, patients with active ulcerative colitis (Lichtiger score ≥ 4) were eligible if initiating systemic corticosteroids.
Background: Corticosteroids are used for induction of remission in patients with moderately to severely active ulcerative colitis. However, up to one-third of patients fail to this therapy. We investigated if fecal microbial composition or its metabolic capacity are associated with response to systemic corticosteroids.
View Article and Find Full Text PDFBackground: Little is known about the bleeding risk in patients with inflammatory bowel disease (IBD) and venous thromboembolism (VTE) treated with anticoagulation. Our aim was to elucidate the rate of major bleeding (MB) events in a well-defined cohort of patients with IBD during anticoagulation after VTE.
Methods: This study is a retrospective follow-up analysis of a multicenter cohort study investigating the incidence and recurrence rate of VTE in IBD.
Use of complementary and alternative medicine and low quality of life associate with the need for psychological and psychotherapeutic interventions in inflammatory bowel disease.
United European Gastroenterol J
February 2021
Introduction: Patients with inflammatory bowel disease (IBD) suffer from various symptoms, impairing their quality of life and often affecting psychosocial issues. This may lead to the need for additional psychological care. This study investigated patients' subjective need for integrated psychosomatic support and psychotherapy and indicators for it.
View Article and Find Full Text PDFArticle Synopsis
- A study investigated the effects of passive smoking on Crohn's disease (CD) in 471 non-smoker patients, revealing that 54% had been exposed to passive smoking.
- Results showed that those exposed to passive smoking had a significantly higher likelihood (67%) of undergoing intestinal surgeries compared to non-exposed patients (30%).
- The analysis indicated that passive smoking is an independent risk factor for such surgeries, with childhood exposure also linked to an increased risk of becoming an active smoker later in life.