Publications by authors named "W Mendenhall"
Objectives: Osteoradionecrosis (ORN) following radiation therapy (RT) is a serious complication for patients undergoing head and neck cancer treatment. Recent literature has found an association between ipsilateral external carotid artery (ECA) diameter and the development of ORN. This study evaluates microvascular free-flap arterial anastomosis diameter and the development of ORN.
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- Locally recurrent nasopharyngeal carcinoma (NPC) poses significant treatment challenges due to the absence of standardized guidelines for postoperative re-irradiation (re-RT).
- This article reviews international recommendations for managing resectable cases of locally recurrent NPC, focusing on re-RT strategies and addressing controversial issues like surgical margins and resectability criteria.
- The consensus suggests a clearer definition of resectability, optimal re-RT doses around 60 Gy, and emphasizes the potential benefits of hyperfractionation to minimize treatment toxicity, aiming to improve patient outcomes.
Purpose: Adenoid cystic carcinoma (ACC) is a rare malignancy accounting for 1% of all head and neck cancers. Treatment for ACC has its challenges and risks, yet few outcomes studies exist. We present long-term outcomes of patients with ACC of the head and neck treated with proton therapy (PT).
View Article and Find Full Text PDFBackground: Patients with head and neck cancer (HNC) may experience substantial anatomical changes during the course of radiotherapy treatment. The implementation of adaptive radiotherapy (ART) proves effective in managing the consequent impact on the planned dose distribution.
Methods: This narrative literature review comprehensively discusses the diverse strategies of ART in HNC and the documented dosimetric and clinical advantages associated with these approaches, while also addressing the current challenges for integration of ART into clinical practice.
Radiotherapy is one of the mainstay treatment modalities for the management of non-metastatic head and neck cancer (HNC). Notable improvements in treatment outcomes have been observed in the recent decades. Modern radiotherapy techniques, such as intensity-modulated radiotherapy and charged particle therapy, have significantly improved tumor target conformity and enabled better preservation of normal structures.
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