Publications by authors named "W Marty Blom"

Background: Climate change is expected to elevate exposure to several environmental health risk factors, including extreme environmental temperatures, air pollution and airborne allergenic pollen. Given their interconnected effects on respiratory and cardiovascular diseases, it is crucial to evaluate these exposures simultaneously. Yet, comprehensive efforts to do so remain limited.

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Background: Sesame is a significant food allergen causing severe and even fatal reactions. Given its increasing prevalence in western diet, sesame is listed as an allergenic food requiring labeling in the United States and EU. However, data on the population reaction doses to sesame are limited.

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Lack of guidance regarding selection of food intake values for allergen risk assessment can lead to different outcomes for similar levels of allergens in food products. Several food consumption survey databases (United States, North-West Europe, and Netherlands) were analyzed to identify optimal food intake percentiles using a sensitivity analysis. Deterministic risk assessment scenarios using the 50th percentile up to the maximum intake per food group were compared with probabilistic risk assessment outcomes.

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Article Synopsis
  • The study updates the Eliciting Doses (ED) for milk allergies using new data from 247 food challenge studies, enhancing the risk assessment for cow's milk-allergic individuals.* -
  • The revised ED values indicate that 1% and 5% of milk-allergic people could react to doses of 0.3 mg and 3.2 mg of milk protein, slightly higher than previously established thresholds but still within the confidence interval.* -
  • This research aids in global food allergen risk assessment efforts and provides important insights for future studies on milk allergy management and safety evaluations.*
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