Natural products as Nrf2 modulators for ferroptosis inhibition in renal disease therapy: Recent progress and future prospects.

Background: The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2, NFE2L2) is a pivotal regulator of redox balance, metabolism, protein homeostasis and inflammation. Nrf2 is critically involved in both ferroptosis and renal diseases, and may serve as a significant target for many natural products in the treatment of renal diseases. However, a comprehensive overview on this topic is still lacking.

Conference 2024: Building an innovative scientific research ecosystem for microbiome and One Health.

The Conference 2024 provides a platform to promote the development of an innovative scientific research ecosystem for microbiome and One Health. The four key components - Technology, Research (Biology), Academic journals, and Social media - form a synergistic ecosystem. Advanced technologies drive biological research, which generates novel insights that are disseminated through academic journals.

A nucleoside-modified rabies mRNA vaccine induces long-lasting and comprehensive immune responses in mice and non-human primates.

Rabies is a lethal zoonotic infectious disease. Vaccines against the rabies virus have significantly reduced the number of deaths from the disease. However, all the licensed rabies vaccines are inactivated vaccines, which have limited immunogenicity and complicated immunization procedures.

Inhibition of pterygium cell fibrosis by the Rho kinase inhibitor.

Pterygium is an ocular disease in which the conjunctival tissue invades the cornea. When the pterygium tissue reaches the pupillary region, the visual function of the patient is affected. Currently, surgical removal is the only effective treatment.

Efficient Photocatalytic Removal of Aqueous Ammonia Nitrogen by g-CN/CoP Heterojunctions Under Visible Light Illumination.

With the development of industry, agriculture, and aquaculture, excessive ammonia nitrogen mainly involving ionic ammonia (NH) and molecular ammonia (NH) has inevitable access to the aquatic environment, posing a severe threat to water safety. Photocatalytic technology shows great advantages for ammonia nitrogen removal, such as its efficiency, reusability, low cost, and environmental friendliness. In this study, CP (g-CN/CoP) composite materials, which exhibited high-efficiency ammonia nitrogen removal, were synthesized through a simple self-assembly method.