Publications by authors named "W Manzanares"
Article Synopsis
- Micronutrient (MN) alterations in critically ill patients can lead to complications, but improving MN status may help as a supportive therapy.
- This review, done by a specialized group, focuses on individual important MNs, such as vitamins A, B, C, D, E, as well as minerals like iron and zinc, to guide future research.
- It emphasizes that high-dose single MN treatments are not advised; instead, patients should receive daily basal needs, with adjustments for higher requirements and treatment for deficiencies, and lists ongoing trials and future research priorities.
Background & Aims: The Global Leadership Initiative on Malnutrition (GLIM) approach to malnutrition diagnosis is based on assessment of three phenotypic (weight loss, low body mass index, and reduced skeletal muscle mass) and two etiologic (reduced food intake/assimilation and disease burden/inflammation) criteria, with diagnosis confirmed by fulfillment of any combination of at least one phenotypic and at least one etiologic criterion. The original GLIM description provided limited guidance regarding assessment of inflammation and this has been a factor impeding further implementation of the GLIM criteria. We now seek to provide practical guidance for assessment of inflammation in support of the etiologic criterion for inflammation.
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- * A working group created consensus-based guidelines to improve the assessment of inflammation in malnutrition, culminating in seven key guidance statements with 99% agreement in the final review.
- * Recommendations include using clinical judgment alongside C-reactive protein (CRP) measurements to assess inflammation, highlighting the importance of understanding the context of CRP readings in diagnostics.
Introduction: The Surviving Sepsis Campaign was developed to improve outcomes for all patients with sepsis. Despite sepsis being the primary cause of death after thermal injury, burns have always been excluded from the Surviving Sepsis efforts. To improve sepsis outcomes in burn patients, an international group of burn experts developed the Surviving Sepsis After Burn Campaign (SSABC) as a testable guideline to improve burn sepsis outcomes.
View Article and Find Full Text PDFIntroduction: In 2020 the pandemic caused by SARS-COV-2 demanded an enormous number of healthcare resources in order to guarantee adequate treatment and support for those patients. This study aims to assess caloric and protein intake and evaluate its associations with relevant clinical outcomes in critically ill with coronavirus disease (COVID-19) patients.
Methods: A nationwide, multicentre prospective observational study including twelve Argentinian intensive care units (ICUs,) was conducted between March and October 2020.