Publications by authors named "W Malter"
Purpose: To evaluate the cost utility of a 9-month supervised exercise program for patients with metastatic breast cancer (mBC), compared with control (usual care, supplemented with general activity advice and an activity tracker). Evidence on the cost-effectiveness of exercise for patients with mBC is essential for implementation in clinical practice and is currently lacking.
Methods: A cost-utility analysis was performed alongside the multinational PREFERABLE-EFFECT randomized controlled trial, conducted in 8 centers across Europe and Australia.
Background/aim: This study examined the influence of preoperative MRI on the choice of implant volume in patients undergoing subcutaneous mastectomy with immediate breast reconstruction. It was postulated that preoperative MRI scans can adequately estimate glandular tissue, which in turn correlates with implant size.
Patients And Methods: Preoperative and postoperative MRI scans were used in oncological and prophylactical subcutaneous mastectomy scenarios in 67 cases at the Department of Gynaecology, Breast Cancer Center, University of Cologne, Germany.
Physical exercise both during and after curative cancer treatment has been shown to reduce side effects. Evidence in the metastatic cancer setting is scarce, and interventions that improve health-related quality of life (HRQOL) are much needed for patients with metastatic breast cancer (MBC). The multinational randomized controlled PREFERABLE-EFFECT trial assessed the effects of exercise on fatigue and HRQOL in patients with MBC.
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- Breast cancer patients often face significant side effects from treatment, including reduced muscle strength and quality of life, but exercise, particularly resistance training, has shown positive outcomes.
- A study involved 40 patients undergoing chemotherapy, with half participating in a high-intensity resistance training program while the other half received standard care.
- Results indicated that those who engaged in the resistance training saw significant improvements in strength and quality of life, suggesting that tailored exercise programs should be further explored in future research.
Article Synopsis
- * An animal model using chicken breast was created to simulate breast tissue, where both ruptured and intact implants were tested with elastography techniques.
- * Results indicated that while shear wave elastography didn't show significant differences between implant types, strain elastography displayed distinct patterns that could aid in accurately diagnosing ruptures.