Publications by authors named "W M Tsui"
The discovery of circulating fetal and tumor cell-free DNA (cfDNA) molecules in plasma has opened up tremendous opportunities in noninvasive diagnostics such as the detection of fetal chromosomal aneuploidies and cancers and in posttransplantation monitoring. The advent of high-throughput sequencing technologies makes it possible to scrutinize the characteristics of cfDNA molecules, opening up the fields of cfDNA genetics, epigenetics, transcriptomics, and fragmentomics, providing a plethora of biomarkers. Machine learning (ML) and/or artificial intelligence (AI) technologies that are known for their ability to integrate high-dimensional features have recently been applied to the field of liquid biopsy.
View Article and Find Full Text PDFMany factors can affect delivery mode decisions. Therefore, this study aimed to explore the effects of maternal age, physician's sex, region, income, and hospital type on cesarean section (C/S) delivery rates between 2008 and 2018 in Taiwan. In this population-based cross-sectional study, data were extracted from the Taiwan National Health Insurance Research Database (2 million individuals).
View Article and Find Full Text PDFAnterior Colporrhaphy and Paravaginal Repair for Anterior Compartment Prolapse: A Review.
Medicina (Kaunas)
November 2024
Article Synopsis
- * Two key surgical techniques for treating anterior vaginal wall prolapse are anterior colporrhaphy, which tightens weakened tissues, and paravaginal repair, which reattaches the vaginal wall to its supportive structures.
- * The review compares these methods in terms of effectiveness, recurrence rates, and complications, suggesting that while anterior colporrhaphy is prevalent, paravaginal repair may yield better outcomes for lateral defects and discussing advancements like minimally invasive surgery options.
Background: Gastric intestinal metaplasia (IM) is a precancerous stage spanning a morphological spectrum that is poorly represented by human cell line models.
Objective: We aim to establish and characterise human IM cell models to better understand IM progression along the cancer spectrum.
Design: A large human gastric IM organoid (IMO) cohort (n=28), their clonal derivatives and normal gastric organoids (n=42) for comparison were established.
Article Synopsis
- * Data was collected from patients who underwent these surgeries at a hospital in Taiwan over a nine-year period, analyzing pre- and post-operative improvements using Pelvic Organ Prolapse Quantification (POP-Q) scores.
- * The findings indicated that both surgical methods resulted in significant improvements, but there were no major differences in outcomes or estimated blood loss, although PVR took longer to perform.