The First Kleinman-type Second-Harmonic Generation Circular Dichroism On/Off Switchable Ferroelectrics.

Chiral ferroelectrics have recently received considerable interest due to their unique chiroptical properties. They can adopt Kleinman symmetry second-harmonic generation (SHG)-active chiral-polar point groups in the ferroelectric phase while Kleinman symmetry SHG-inactive chiral-nonpolar point groups in the paraelectric phase, providing a great opportunity to realize on/off switching of SHG circular dichroism (SHG-CD) response. However, the SHG-CD effect was rarely explored in chiral ferroelectrics, and the on/off switchable SHG-CD has never been reported.

Assembly of ceria-Nrf2 nanoparticles as macrophage-targeting ROS scavengers protects against myocardial infarction.

Myocardial infarction (MI) is a leading cause of morbidity and mortality worldwide, and mitigating oxidative stress is crucial in managing MI. Nuclear factor erythroid 2-related factor 2 (Nrf2) plays a critical role in combating oxidative stress and facilitating cardiac remodeling post-MI. Here, we engineered Cerium oxide (CeO) nanoparticle-guided assemblies of ceria/Nrf2 nanocomposites to deliver Nrf2 plasmids.

International youth football research developments: A CiteSpace-based bibliometric analysis.

With the vigorous development of football, research on youth football has garnered significant attention from scholars, leading to an increase in published findings. However, there is currently no comprehensive retrospective study that examines the status, hotspots, and trends of research in this field. This study employed Cite Space, a visual bibliometric software, to systematically review and analyze 1637 articles from the Web of Science (WOS) and China Knowledge Infrastructure Project (CNKI) databases up to January 2024.

Design, Current States, and Challenges of Nanomaterials in Anti-Neuroinflammation: A Perspective on Alzheimer's Disease.

Alzheimer's disease (AD), an age-related neurodegenerative disease, brings huge damage to the society, to the whole family and even to the patient himself. However, until now, the etiological factor of AD is still unknown and there is no effective treatment for it. Massive deposition of amyloid-beta peptide(Aβ) and hyperphosphorylation of Tau proteins are acknowledged pathological features of AD.