Publications by authors named "W M Leisenring"
Purpose: Melanoma as a subsequent malignant neoplasm has been described among childhood cancer survivors; however, the risk factors and long-term survival are not well understood.
Methods: We assessed incidence, risk factors, and outcomes for melanoma among participants in the Childhood Cancer Survivor Study cohort. Cumulative incidence and standardized incidence ratios (SIRs) were calculated, and multivariable Cox models were used to determine hazard ratios (HRs) and associated 95% CI for melanoma risk factors.
Background: Adolescents and young adults with cancer (AYAs, ages 15-39 at the time of diagnosis) experience significant adverse health and psychosocial outcomes. AYAs live with emotional distress and health care demands that exceed those of their healthy peers but can have difficulty accessing care. Digitally delivered interventions are an attractive option for AYA survivors, a population that routinely utilizes online resources when seeking health information and support.
View Article and Find Full Text PDFBackground: While female survivors of Hodgkin lymphoma (HL) have an increased risk of breast cancer (BC), no BC risk prediction model is available. We developed such models incorporating mean radiation dose to the breast or breast quadrant-specific radiation doses.
Methods: Relative risks and age-specific incidence for BC and competing events (mortality or other subsequent cancer) were estimated from 1194 Dutch five-year HL survivors, treated at ages 11-40 during 1965-2000.
Article Synopsis
- Many childhood cancer survivors are at risk for cardiovascular issues and should receive carotid ultrasounds, especially 10 years post neck radiation therapy of 40 Gy or more, according to guidelines.
- A study examined nearly 10,000 childhood cancer survivors, revealing that only 29.7% of those who had high-dose neck radiation had a carotid ultrasound, compared to 10.7% of those who had lower doses and just 4.7% of siblings without cardiovascular conditions.
- Factors like being over 50, recent visits to a cancer specialist, and undergoing other tests, like colonoscopies or echocardiograms, increase the likelihood of having a carotid ultrasound among these survivors.