Publications by authors named "W M J Schreurs"
Introduction: Multidisciplinary teams treating patients with newly diagnosed Colorectal Cancer (CRC) often encounter the appearance of Indeterminate Pulmonary Nodules (IPNs) that warrants follow-up with repetitive medical imaging and anxiety for patients. We determined the incidence of IPNs in patients with newly diagnosed CRC and developed and validated a model for individualized risk prediction of IPNs being lung metastases.
Material And Methods: Newly diagnosed CRC who underwent surgery between November 2011 to June 2014 were included to create the risk model, developed using both clinical experience and statistical selection.
Article Synopsis
- In the Netherlands, the use of neoadjuvant radiotherapy for rectal cancer decreased significantly from 2011 to 2016 following a guideline revision, raising concerns about the treatment of locally recurrent rectal cancer (LRRC).
- A study compared two national cohorts from 2011 and 2016, analyzing outcomes such as time to LRRC, metastasis presence, treatment intent, and survival rates.
- Despite the decline in neoadjuvant treatment, the rates of LRRC remained similar, but patients in 2016 had a greater chance of receiving curative treatments and showed improved two-year survival rates after developing LRRC.
Background: Pulmonary metastasectomy and stereotactic ablative radiotherapy (SABR) are both guideline-recommended treatments for selected patients with oligometastatic colorectal pulmonary metastases. However, there is limited evidence comparing these local treatment modalities in similar patient groups.
Methods: We retrospectively reviewed records of consecutive patients treated for colorectal pulmonary metastases with surgical metastasectomy or SABR from 2012 to 2019 at two Dutch referral hospitals that had different approaches toward the local treatment of colorectal pulmonary metastases, one preferring surgery, the other preferring SABR.
Article Synopsis
- Local control for colorectal pulmonary metastases after stereotactic ablative radiotherapy (SABR) is lower compared to other tumors, but salvage surgery can be effective.
- The study involved 17 patients who underwent 20 salvage surgeries, with 14 being minimally invasive, demonstrating a median overall survival of 71 months post-surgery.
- Despite some complications (20% had significant issues), the results suggest that salvage resection is a viable option with favorable outcomes for selected patients.