Racial Disparities in Opioid Prescribing in the United States from 2011 to 2021: A Systematic Review and Meta-Analysis.

Background: This meta-analysis is an update to a seminal meta-analysis on racial/ethnic disparities in pain treatment in the United States (US) published in 2012. Since then, literature has accumulated on the topic and important policy changes were made.

Objective: Examining racial/ethnic disparities in pain management and investigating key moderators of the association between race/ethnicity and pain outcomes in the US.

Cannabis Use and Anesthesia.

Consistent evidence supporting the use of cannabinoids for management of acute pain is lacking. A small number of observational studies suggest cannabinoid use is associated with reduced opioid use but pain scores remain unchanged. The majority of randomized trials involving a variety of cannabinoid compounds have shown no benefit for acute pain.

Illicitly Manufactured Fentanyl: Anesthesia's Role in the Perioperative Setting.

In wave 4 of the opioid crisis, which is dominated by illicitly manufactured fentanyl (IMF) and stimulant use, anesthesia personnel could play an important role in the perioperative care of these persons. Knowledge of the extent and lethality of opioid use in the current wave of the opioid crisis could raise awareness of the problem among anesthesia personnel. In the absence of research to guide development of best practice recommendations, knowledge of the historical trends in opioid use, the epidemiology of IMF use, and pragmatic clinically-oriented approaches for identifying persons using IMF could provide a general framework for future research.