Publications by authors named "W M Edmunds"
The Impact of Public Health and Social Measures (PHSMs) on SARS-CoV-2 Transmission in the WHO European Region (2020-2022).
Influenza Other Respir Viruses
December 2024
Background: Between 2020 and 2022, countries used a range of different public health and social measures (PHSMs) to reduce the transmission of SARS-CoV-2. The impact of these PHSMs varied as the pandemic progressed, variants of concern (VOCs) emerged, vaccines rolled out and acceptance/uptake rates evolved. In this study, we assessed the impact of PHSMs in the World Health Organization (WHO) European Region during VOC phases.
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- The study investigated the effectiveness and safety of the rVSV-ZEBOV vaccine against Zaire Ebolavirus disease among contacts of EVD survivors, focusing on the influence of pre-existing immunity on vaccination outcomes.
- Ten percent of participants had pre-existing antibodies, but both those with and without antibodies showed significant increases in IgG levels post-vaccination, indicating strong immune responses.
- The findings support the vaccine's safety and suggest that pre-vaccination antibody screening is unnecessary, as it does not negatively impact the immune response to the vaccine.
During 2020-2022, players and staff in the English Premier League in the United Kingdom were tested regularly for SARS-CoV-2 with the aim of creating a biosecure bubble for each team. We found that prevalence and reinfection estimates were consistent with those from other studies and with community infection trends.
View Article and Find Full Text PDFProphylactic drugs against dengue are currently under development. In this study, we explored how such prophylactic approaches might affect dengue cases in four communes of Nha Trang City, Vietnam. A community level dengue transmission survey indicated high levels of previous exposure to dengue (89.
View Article and Find Full Text PDFWe evaluated the spatiotemporal clustering of rapid diagnostic test-positive cholera cases in Uvira, eastern Democratic Republic of the Congo. We detected spatiotemporal clusters that consistently overlapped with major rivers, and we outlined the extent of zones of increased risk that are compatible with the radii currently used for targeted interventions.
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