Publications by authors named "W M Alkhojali"
In silico elucidation of plausible anti-obesity activity by Withaferin-A compound targeting alpha-amylase.
Eur Rev Med Pharmacol Sci
April 2023
Article Synopsis
- The study evaluated Withaferin-A's interaction with the drug target α-amylase using a computational approach to determine its inhibitory potential and mechanisms of action.
- Various computational methods, including molecular dynamics simulations and docking, were employed to investigate the atomic-level details and pharmacological properties of Withaferin-A derived from W. somnifera.
- Results showed a strong binding affinity of Withaferin-A to α-amylase, identifying key molecular interactions that could inform future research on designing α-amylase inhibitors for potential anti-obesity applications.