Publications by authors named "W Legnani"

The aim of this study is to formulate a new methodology based upon informational tools to detect patients with cardiac arrhythmias. As it is known, sudden death is the consequence of a final arrhythmia, and here lies the relevance of the efforts aimed at the early detection of arrhythmias. The information content in the time series from an electrocardiogram (ECG) signal is conveyed in the form of a probability distribution function, to compute the permutation entropy proposed by Bandt and Pompe.

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Introduction: A comparison among two blood pressure pulse propagation models has made in this work. One of them is a traditional model based upon the Navier Stockes equations in one spatial dimension, the one along the direction of the arteries (from here NS1D), the other is based the concept of soliton propagation using the Korteweg De Vries equation (named KdV).

Methods: The arterial three is assumed a long successive connection of serial segments of arteries, at the inlet of the network (close up to the aorta), an acquired pulse, in vivo, wave is imposed.

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In the present work, an ischaemic process, mainly focused on the reperfusion stage, is studied using the informational causal entropy-complexity plane. Ischaemic wall behavior under this condition was analyzed through wall thickness and ventricular pressure variations, acquired during an obstructive flow maneuver performed on left coronary arteries of surgically instrumented animals. Basically, the induction of ischaemia depends on the temporary occlusion of left circumflex coronary artery (which supplies blood to the posterior left ventricular wall) that lasts for a few seconds.

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Arterial pressure waves have been described in one dimension using several approaches, such as lumped (Windkessel) or distributed (using Navier-Stokes equations) models. An alternative approach consists of modeling blood pressure waves using a Korteweg-de Vries (KdV) equation and representing pressure waves as combinations of solitons. This model captures many key features of wave propagation in the systemic network and, in particular, pulse pressure amplification (PPA), which is a mechanical biomarker of cardiovascular risk.

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Models define a simplification of reality, which help to understand function. The arterial system has been modeled in many ways: lumped models, tube models and anatomically based distributed models. In this work, arterial segments were modeled as thin nonlinear elastic tubes filled with an incompressible fluid, whose governing dynamics were denoted by the Korteweg and DeVries equation.

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