Phosphaturic mesenchymal tumor (PMT) is a rare benign mesenchymal tumor characterized by excessive secretion of fibroblast growth factor 23 (FGF23), leading to phosphate loss and systemic osteomalacia. Despite recent progress in PMT research, no consensus on diagnosis and treatment guidelines has been established. This case series describes the clinical and pathological features of six pathologically confirmed PMT patients treated at the Third Affiliated Hospital of Sun Yat-sen University from 2010 to 2024, aiming to provide new insights for the management of this condition.
View Article and Find Full Text PDFThe aim of this study was to explore application of visible and near-infrared (Vis/NIR) spectroscopy combined with machine learning models for SSC and TA prediction of hybrid citrus. The Vis/NIR spectra of samples including navel-region, equator-region and multi-region combination spectra in navel-region and equator-region were collected using a benchtop equipment. The performance of SSC and TA prediction models with different region spectra, including partial least squares (PLS), random forest (RF), k-nearest neighbors (KNN), support vector machine (SVM) and multilayer feedforward neural network (MFNN), was assessed.
View Article and Find Full Text PDFDNA2, a multifunctional enzyme with structure-specific nuclease, 5 -to-3 helicase, and DNA-dependent ATPase activities, plays a pivotal role in the cellular response to DNA damage. However, its involvement in cerebral ischemia/reperfusion (I/R) injury remains to be elucidated. This study investigated the involvement of DNA2 in cerebral I/R injury using conditional knockout (cKO) mice ( -Cre) subjected to middle cerebral artery occlusion (MCAO), an established model of cerebral I/R.
View Article and Find Full Text PDFBackground: Population aging and smoking are both major challenges worldwide, particularly in developing countries. We preliminarily explored the relationship of smoking cessation duration and cognitive function among middle-aged and older Chinese.
Methods: The data comes from China Health and Retirement Longitudinal Study (CHARLS) wave 4.
Renewable energy-powered seawater electrolysis is a green and attractive technique for producing high-purity hydrogen. However, severe chlorideions (Cl) and their derivatives tend to corrode anodic catalysts at ampere-level current densities and hinder the application of seawater-to-H systems. Herein, a polycalmagite (PCM)-coated NiFe layered double hydroxide is presented on Ni foam (NiFe LDH@PCM/NF) that exhibits exceptional stability in alkaline seawater.
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