Publications by authors named "W L Wheeler"

Introduction: Tobacco industry offers price promotions to promote cigarette smoking. Several social identities (e.g.

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As more multi-ancestry GWAS summary data become available, we have developed a comprehensive trans-ancestry pathway analysis framework that effectively utilizes this diverse genetic information. Within this framework, we evaluated various strategies for integrating genetic data at different levels-SNP, gene, and pathway-from multiple ancestry groups. Through extensive simulation studies, we have identified robust strategies that demonstrate superior performance across diverse scenarios.

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Article Synopsis
  • - The study investigates how genetic variants affect the relationship between heavy alcohol consumption and the risk of pancreatic cancer, utilizing data from a sizable European ancestry population.
  • - Researchers identified a new relevant genomic region (10p11.22) linked to pancreatic cancer risk and a specific SNP (rs7898449) that suggests this association is influenced by heavy alcohol consumption.
  • - The findings highlight the potential role of the neuropilin 1 gene in pancreatic cancer development, offering new insights into cancer risk factors, especially among heavy drinkers.
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is a genus of ubiquitous pigmented yeast found in the environment and as a commensal of human and animal microbiota. Previously considered nonpathogenic, has emerged as an important cause of nosocomial and opportunistic infections in susceptible patients. While spp.

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