Publications by authors named "W L Weaver"
While flowering plants have diversified in virtually every terrestrial clime, climate constrains the distribution of individual lineages. Overcoming climatic constraints may be associated with diverse evolutionary phenomena including whole genome duplication (WGD), gene-tree conflict, and life-history changes. Climatic shifts may also have facilitated increases in flowering plant diversification rates.
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- - Vaccinieae is a diverse group within the Ericaceae family, consisting of about 1430 species, primarily tropical, but well-known for temperate crops like blueberries and cranberries.
- - A phylogenomic study of 210 species revealed that Vaccinieae likely originated in temperate North America around 30 million years ago, with tropical species resulting from multiple migrations from these northern ancestors.
- - Findings indicate significant evolutionary events, including a unique ovary structure development and a major polyploid event, suggesting that Vaccinium's classification needs reevaluation due to its complex evolutionary history.
Current antigen delivery platforms, such as alum and nanoparticles, are not readily tunable, thus may not generate optimal adaptive immune responses. We created an antigen delivery platform by loading lyophilized Microporous Annealed Particle (MAP) with aqueous solution containing target antigens. Upon administration of antigen loaded MAP (VaxMAP), the biomaterial reconstitution forms an instant antigen-loaded porous scaffold area with a sustained release profile to maximize humoral immunity.
View Article and Find Full Text PDFCurrent antigen delivery platforms, such as alum and nanoparticles, are not readily tunable, thus may not generate optimal adaptive immune responses. We created an antigen delivery platform by loading lyophilized Microporous Annealed Particle (MAP) with aqueous solution containing target antigens. Upon administration of antigen loaded MAP (VaxMAP), the biomaterial reconstitution forms an instant antigen-loaded porous scaffold area with a sustained release profile to maximize humoral immunity.
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