Publications by authors named "W L Lowrance"
Background: The psychological and cardiovascular health impacts on family members of patients who have been diagnosed with cancer have not been well characterized. The purpose of this study is to determine whether a family member's cancer diagnosis influences the risk of psychological illness and cardiovascular disease in first-degree relatives and spouses of patients affected by cancer.
Methods: This retrospective cohort analysis evaluated the risk of psychological illness and cardiovascular disease in first-degree relatives and spouses of patients diagnosed with a genitourinary cancer between 1990 and 2015 compared to relatives of those not diagnosed with a genitourinary cancer.
Background: Although radical cystectomy (RC) is the standard of care for patients with bacillus Calmette-Guérin (BCG)-unresponsive high-risk non-muscle-invasive bladder cancer (NMIBC), many patients are ineligible for surgery or elect bladder preservation.
Objective: To evaluate the efficacy and safety of atezolizumab in BCG-unresponsive high-risk NMIBC.
Design, Setting, And Participants: This was a single-arm phase 2 trial in patients with BCG-unresponsive high-risk NMIBC who were ineligible for or declined RC.
Purpose: In 2022 the American Urological Association (AUA) requested an Update Literature Review (ULR) to incorporate new evidence generated since the 2020 publication of this guideline. The resulting 2023 Guideline Amendment addresses updated recommendations for patients with advanced prostate cancer.
Materials And Methods: The ULR addressed 23 of the original 38 guideline statements and included an abstract-level review of eligible studies published since the 2020 systematic review.
Article Synopsis
- A study was conducted to evaluate the impact of the Choosing Wisely campaign on the use of imaging for men with newly diagnosed prostate cancer, focusing on reducing unnecessary procedures.
- Analysis of Medicare data from 2007 to 2015 showed a significant decrease in imaging utilization among low-risk patients, with declines in CT and nuclear medicine bone scans.
- Although the campaign has led to a decrease in unnecessary imaging for low-risk patients, imaging for high-risk patients remains high, suggesting ongoing challenges in promoting guideline-concordant care.
Background: To determine the feasibility of using wearables in patients undergoing radical cystectomy to monitor postoperative heart rate and activity and attempt to correlate these factors to complications and readmissions.
Materials And Methods: We conducted a prospective study of 20 patients undergoing radical cystectomy for bladder cancer between June 2017 and March 2018. Each patient was provided with a Garmin Vívofit heart rate (HR) activity tracker and instructed to wear it on their wrist for 30 days postoperatively.