San Huang Xiao Yan recipe promoted wound healing in diabetic ulcer mice by inhibiting Th17 cell differentiation.

Ethnopharmacological Relevance: Diabetic ulcer is a serious diabetes complication and a primary reason for amputations. For many years, the San Huang Xiao Yan (SHXY) recipe has served as a conventional remedy for these ulcers, effectively reducing inflammatory factors and exhibiting considerable therapeutic efficacy. However, the precise mechanism remains incompletely understood.

Skin Effect of Nonlinear Optical Responses in Antiferromagnets.

Nonlinear optics plays important roles in the research of fundamental physics and the applications of high-performance optoelectronic devices. The bulk nonlinear optical responses arise from the uniform light absorption in noncentrosymmetric crystals, and hence are usually considered to be the collective phenomena of all atoms. Here we show, in contrast to this common expectation, the nonlinear optical responses in antiferromagnets can be selectively accumulated near the surfaces, representing a skin effect.

Enhancing the tribopositive characteristics of polyvinyl alcohol (PVA)-carbon composites by optimizing the PVA-carbon interaction with various carbon fillers.

Incorporating carbon-based fillers into triboelectric nanogenerators, TENGs, is a compelling strategy to enhance the power output. However, the lack of systematic studies comparing various carbon fillers and their impact on tribopositive contact layers necessitates further research. To address these concerns, various carbon fillers (including buckminsterfullerene (C), graphene oxide (GO), reduced graphene oxide (rGO), multi-wall carbon nanotube (MWCNT), and super activated carbon (SAC)) with distinct structural and electrical properties are mixed with polyvinyl alcohol, PVA, to form PVA-carbon composites and used as tribopositive layers in the contact-separation of TENGs.

Association between serum uric acid and all-cause and cardiovascular-related mortality in hemodialysis patients.

Background: The association between serum uric acid (UA) and all-cause and cardiovascular-related mortality in hemodialysis (HD) patients is conflicting. We investigated this association and explored the effect modification of underlying nutritional status, as reflected in the lean tissue index (LTI) and the Geriatric Nutritional Risk Index (GNRI), which serve as markers of muscle mass and nutritional risk in HD patients.

Methods: A retrospective cohort study was conducted from January 2019 to December 2023.

Staphylococcus aureus regulates Th17 cells and autophagy via STING in chronic eosinophilic rhinosinusitis with nasal polyps.

Purpose: As a common pathogen of rhinosinusitis, the role of Staphylococcus aureus in modulating autophagy through STING activation and Th17 cell differentiation in CRSwNP remains unexplored. This study aims to investigate how S. aureus regulates Th17 cell differentiation and the occurrence and development of autophagy in CRS by inducing STING expression.