Publications by authors named "W L Fangman"
Eukaryotic origins of DNA replication undergo activation at various times in S-phase, allowing the genome to be duplicated in a temporally staggered fashion. In the budding yeast Saccharomyces cerevisiae, the activation times of individual origins are not intrinsic to those origins but are instead governed by surrounding sequences. Currently, there are two examples of DNA sequences that are known to advance origin activation time, centromeres and forkhead transcription factor binding sites.
View Article and Find Full Text PDFObjective: The number of registered motorcycles in the United States has been steadily increasing, as have the number of motorcycle injuries and fatalities. The Midwest has the lowest incidence of helmet use in the country. Iowa in particular has no helmet law.
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- Intralesional and intra-articular corticosteroids are frequently used in dermatology, orthopedic surgery, and rheumatology for various conditions.
- A 32-year-old woman developed bilateral hypopigmented patches after receiving corticosteroids for de Quervain's tendonitis, with a later unilateral extension of these patches.
- A biopsy showed intact melanocytes, suggesting that the hypopigmentation is due to reduced melanocyte function rather than loss of the cells themselves, although the exact mechanism remains unclear.