Publications by authors named "W Krupski"
Mastocytosis is a heterogeneous group of disorders, characterized by accumulation of clonal mast cells which can infiltrate several organs, most often spine (70%). The pathogenesis of mastocytosis bone disease is poorly understood. The main aim of the study was to investigate whether neoplastic mast cells may be the source of sclerostin and whether there is an association between sclerostin and selected bone remodeling markers with mastocytosis related bone disease.
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- A 24-year-old man from Zimbabwe living in Poland experienced abdominal pain, fatigue, and gastrointestinal issues for 3 years, leading to extensive diagnostic testing.
- Tests confirmed he had chronic intestinal schistosomiasis caused by co-infections of Schistosoma intercalatum and Schistosoma mansoni.
- After undergoing two treatment cycles with praziquantel, the patient improved, highlighting the need to recognize rare tropical diseases in individuals from high-endemic regions living abroad.
Introduction And Objective: CT examination is an important diagnostic tool in assessment of the severity of the infection and course of the disease. The aim of the study was to evaluate the degree and frequency of involvement of individual lung lobes and the population Lobe Involvement Coefficient (pLIC) value in the investigated population.
Material And Methods: The analyzed material comprised 124 patients aged 18-92 years.
In April 2017 midostaurin was approved by the US Food and Drug Administration for the treatment of patients with aggressive systemic mastocytosis (ASM). So far, very limited real world data on its efficacy is available. Thirteen patients aged from 48 to 79 years, who received midostaurin in the early access program, were included in the study.
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