Publications by authors named "W Kreisel"

Esophageal lichen planus is an underrecognized manifestation of lichen planus. It is typically diagnosed based on characteristic endoscopic findings, such as hyperkeratosis, trachealization, denudation and/or stenosis, along with the presence of a lichenoid infiltrate in histopathological examination. In cases where no other manifestation of lichen planus are found and direct immunofluorescence for fibrinogen along the basement membrane is negative, the term "lichenoid esophagitis" should be preferred.

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Article Synopsis
  • There is currently no established treatment for Eosinophilic Lichen Planus (ELP), and standard therapies for cutaneous Lichen Planus (LP), like retinoids, are ineffective in ELP cases.
  • Topical glucocorticosteroids can help in some cases of esophageal inflammation but are not always effective, leading to the trial of various immunosuppressive therapies with mixed results.
  • The report highlights a severe ELP case that was resistant to multiple treatments, but significant improvement was achieved with the JAK inhibitor tofacitinib, suggesting its potential role in treating this immune-mediated condition.
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It is unclear to what extent systemic arterial blood pressure influences portal pressure. This relationship is clinically important as drugs, which are conventionally used for therapy of portal hypertension, may also influence systemic arterial blood pressure. This study investigated the potential correlation between mean arterial (MAP) and portal venous pressure (PVP) in rats with healthy livers.

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An involvement of the esophagus in patients with lichen planus was described for the first time in 1982. Ever since, it has been seen as a rarity. However, studies over the last 10 years have shown a higher prevalence than expected.

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Lichen planus (LP) is a frequent, chronic inflammatory disease involving the skin, mucous membranes and/or skin appendages. Esophageal involvement in lichen planus (ELP) is a clinically important albeit underdiagnosed inflammatory condition. This narrative review aims to give an overview of the current knowledge on ELP, its prevalence, pathogenesis, clinical manifestation, diagnostic criteria, and therapeutic options in order to provide support in clinical management.

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