Case Report: Administration of Amniotic Fluid-Derived Nanoparticles in Three Severely Ill COVID-19 Patients.

A human coronavirus (HCoV-19) has caused the novel coronavirus disease (COVID-19) outbreak worldwide. There is an urgent need to develop new interventions to suppress the excessive immune response, protect alveolar function, and repair lung and systemic organ damage. Zofin (previously known as Organicell Flow) is a novel therapeutic that is derived from the soluble and nanoparticle fraction (extracellular vesicles and exosomes) of human amniotic fluid.

Mechanical stress measurement by an achromatic optical digital speckle pattern interferometry strain sensor with radial in-plane sensitivity: experimental comparison with electrical strain gauges.

This paper shows the optical setup of a radial in-plane digital speckle pattern interferometer which uses an axis-symmetrical diffractive optical element (DOE) to obtain double illumination. The application of the DOE gives in-plane sensitivity which only depends on the grating period of the DOE instead of the wavelength of the laser used as illumination source. A compact optical layout was built in order to have a portable optical strain sensor with a circular measurement area of about 5 mm in diameter.

Achromatic digital speckle pattern interferometer with constant radial in-plane sensitivity by using a diffractive optical element.

We report on a digital speckle pattern interferometer that applies a binary diffractive optical element (DOE) to generate double illumination and radial in-plane sensitivity. The application of the DOE ensures independence on the wavelength of the laser used as an illumination source. Furthermore, in-plane sensitivity only depends on the grating period of the DOE.

Long-term residual musculoskeletal deficits after femoral shaft fractures treated with intramedullary nailing.

Background: Locked intramedullary (IM) nailing has been recognized as one of the most reliable methods for treatment of femoral shaft fractures. Although IM nails are routinely used in the treatment of these fractures, the long-term effects of retained IM nails are unknown.

Methods: Seventeen patients with radiographically documented healed fracture of femoral diaphysis after locked IM nailing technique were evaluated at a follow-up of at least 18 months postoperatively.

[Legal aspects (with comparative reference to German Law)].

Considering the improved medico-technical possibilities, the treatment of handicapped newborns has weighty consequences for all interested persons. But 'letting die' these infants can never be a solution for this problem. It is not possible to find a reliable test for an authorized withdrawal of vital treatment.