Publications by authors named "W K Logan"
Background: Moyamoya is a progressive, non-atherosclerotic cerebral arteriopathy that may present in childhood and currently has no cure. Early diagnosis is critical to prevent a lifelong risk of neurological morbidity. Blood-oxygen-level-dependent (BOLD) MRI cerebrovascular reactivity (CVR) imaging provides a non-invasive, in vivo measure of autoregulatory capacity and cerebrovascular reserve.
View Article and Find Full Text PDFHuman nature being what it is, individuals engaging in unlawful activity will often seek to avoid having their misconduct detected by law enforcement. This article provides the first legal analysis of what are termed detection avoidance measures, and evaluates whether, and how, they should be subject to criminalization.
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- The use of oral vitamin K antagonists (VKAs) may increase the risk of complications for patients undergoing endovascular thrombectomy (EVT) due to acute ischemic stroke from large vessel occlusion.
- This study retrospectively analyzed data from over 32,000 patients to explore the relationship between recent VKA use and outcomes during EVT.
- Results indicated that while overall prior VKA use was not linked to a significantly higher risk of symptomatic intracranial hemorrhage (sICH), patients with higher INR levels (above 1.7) faced a considerably increased risk compared to those not taking VKAs.
Article Synopsis
- Moyamoya disease is a condition that affects blood flow in the brain, leading to blocked arteries and potential cognitive issues, which have been studied mainly in adults but not much in children.
- A study involving 30 children with moyamoya found that abnormal blood flow, especially in the frontal and parietal regions, correlates with difficulties in executive function and intellectual ability, particularly in those with syndromic moyamoya.
- The findings suggest that certain areas of the brain may help compensate for cognitive challenges, highlighting the importance of understanding regional brain function in children with this disease.